{"id":1287,"date":"2021-02-26T16:54:58","date_gmt":"2021-02-26T21:54:58","guid":{"rendered":"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/"},"modified":"2021-03-23T17:52:01","modified_gmt":"2021-03-23T21:52:01","slug":"sensors-for-fast-medical-and-environmental-analyses","status":"publish","type":"project","link":"https:\/\/demo.irdq.ca\/en\/project\/sensors-for-fast-medical-and-environmental-analyses\/","title":{"rendered":"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES"},"content":{"rendered":"<h3>+RAPID +EFFICIENT<\/h3>\n<p>Modern medicine is moving towards personalized treatment schedules, requiring analytical tools to monitor the response of patients during treatment. Chemotherapy patients are currently administered cocktails of drugs according to a schedule pre-determined by statistical responses of multiple previous patients. This protocol is not optimal. One key chemotherapy agent, methotrexate, has a narrow therapeutic window: low concentrations are ineffective in treating cancer, while high concentrations are unacceptably toxic to the patient. The Masson and Pelletier groups are developing biosensors in which well-characterized Au nanoparticles are patterned on a glass substrate to serve as a colorimetric test strip for detecting methotrexate within minutes by surface plasmon resonance (SPR). The methotrexate-sensing scheme has been validated with a prototype SPR instrument and is now in clinical trials with patients undergoing chemotherapy.<\/p>\n<p>The work is supported by Institut M\u00e9rieux and BioM\u00e9rieux, and the development of related sensors for rapid environmental analyses is being carried out in collaboration with Defense Research and Development Canada. A prototype instrument for the analysis of methotrexate has been built, tested, and shown to be faster, cheaper, and easier to use than current alternatives. Clinical studies of the instrumentation are underway.<\/p>\n<h3>RESEARCHERS<\/h3>\n<p>Prof. Jean-Fran\u00e7ois Masson and Prof. Jo\u00eblle Pelletier (Universit\u00e9 de Montr\u00e9al)<\/p>\n<h3>IRDQ&#8217;S CONTRIBUTION<\/h3>\n<ul>\n<li><a href=\"https:\/\/demo.irdq.ca\/en\/tag-product\/transmission-electron-microscopy-tem\/\">Transmission electron microscopy (TEM)<\/a><\/li>\n<li><a href=\"https:\/\/demo.irdq.ca\/en\/tag-product\/scanning-electron-microscopy-sem\/\">Scanning electron microscopy (SEM)<\/a><\/li>\n<li><a href=\"https:\/\/demo.irdq.ca\/en\/tag-product\/raman-spectroscopy\/\">Raman spectroscopy<\/a><\/li>\n<li><a href=\"https:\/\/demo.irdq.ca\/en\/tag-product\/atomic-force-microscopy-afm\/\">Atomic force microscopy (AFM)<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>+RAPID +EFFICIENT Modern medicine is moving towards personalized treatment schedules, requiring analytical tools to monitor the response of patients during treatment. Chemotherapy patients are currently administered cocktails of drugs according to a schedule pre-determined by statistical responses of multiple previous patients. This protocol is not optimal. One key chemotherapy agent, methotrexate, has a narrow therapeutic [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1279,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":""},"project_category":[655,650,653,654],"project_tag":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES | IRDQ<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES | IRDQ\" \/>\n<meta property=\"og:description\" content=\"+RAPID +EFFICIENT Modern medicine is moving towards personalized treatment schedules, requiring analytical tools to monitor the response of patients during treatment. Chemotherapy patients are currently administered cocktails of drugs according to a schedule pre-determined by statistical responses of multiple previous patients. This protocol is not optimal. One key chemotherapy agent, methotrexate, has a narrow therapeutic [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/\" \/>\n<meta property=\"og:site_name\" content=\"IRDQ\" \/>\n<meta property=\"article:modified_time\" content=\"2021-03-23T21:52:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/bg-card-home-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"510\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/\",\"url\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/\",\"name\":\"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES | IRDQ\",\"isPartOf\":{\"@id\":\"https:\/\/demo.irdq.ca\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/bg-card-home-2.jpg\",\"datePublished\":\"2021-02-26T21:54:58+00:00\",\"dateModified\":\"2021-03-23T21:52:01+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/#primaryimage\",\"url\":\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/bg-card-home-2.jpg\",\"contentUrl\":\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/bg-card-home-2.jpg\",\"width\":640,\"height\":510},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/demo.irdq.ca\/project\/capteurs-pour-analyses-medicales-ou-environnementales-rapides\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/demo.irdq.ca\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Projets\",\"item\":\"https:\/\/demo.irdq.ca\/project\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/demo.irdq.ca\/#website\",\"url\":\"https:\/\/demo.irdq.ca\/\",\"name\":\"IRDQ\",\"description\":\"Infrastructure en recherche et d\u00e9veloppement du Qu\u00e9bec\",\"publisher\":{\"@id\":\"https:\/\/demo.irdq.ca\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/demo.irdq.ca\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/demo.irdq.ca\/#organization\",\"name\":\"IRDQ\",\"url\":\"https:\/\/demo.irdq.ca\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/demo.irdq.ca\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/irdq-logo-vertical.png\",\"contentUrl\":\"https:\/\/demo.irdq.ca\/wp-content\/uploads\/2021\/02\/irdq-logo-vertical.png\",\"width\":1705,\"height\":683,\"caption\":\"IRDQ\"},\"image\":{\"@id\":\"https:\/\/demo.irdq.ca\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES | IRDQ","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"SENSORS FOR FAST MEDICAL AND ENVIRONMENTAL ANALYSES | IRDQ","og_description":"+RAPID +EFFICIENT Modern medicine is moving towards personalized treatment schedules, requiring analytical tools to monitor the response of patients during treatment. 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